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Ozempic vs Saxenda

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Summary

Saxenda and Ozempic are FDA-approved for weight loss, but have different uses: Saxenda for weight management and Ozempic for diabetes. Saxenda is taken daily (0.6 mg to 3 mg), while Ozempic is weekly (0.5 mg to 1 mg). Side effects include nausea, diarrhea, and low blood sugar. Saxenda costs £250-£299 monthly, Ozempic about £170-£200.

Saxenda and Ozempic are both prescription drugs approved by the U.S. Food and Drug Administration and both belong to a class of medication called glucagon-like peptide-1 receptor agonists, which require subcutaneous injection. Despite their similarities, Saxenda is approved solely as a weight loss medication while Ozempic is licensed for diabetes management. When it comes to dosage, Saxenda doses range from 0.6 mg to 3 mg while Ozempic doses range from 0.5 mg to 1 mg (or up to 2 mg for some patients). Furthermore, Saxenda is a daily injection whereas Ozempic is a once-weekly injection depending on your doctor’s instructions. Ultimately, each medication offers its benefits and potential risks for each patient so it’s important that you consult with your healthcare provider about what would work best for you before making any treatment decisions.

Side Effects

As Saxenda and Ozempic are from the same medication class, known as GLP-1 receptor agonists, they have largely similar side effects. The most common side effects reported include nausea, diarrhoea, headache, stomach pain, vomiting, constipation, and low blood sugar levels. Since everyone will react differently to any given medication, it is hard to say which medication has fewer side effects overall.

Some people might find one of the two medications more tolerable than the other. They may experience fewer or milder side effects with one over the other due to their individual chemistry and body type. Ultimately it is up to you and your doctor to decide which treatment option is best for you based on how your body responds to the various drugs. It is important to monitor yourself while taking these injectable medications and discuss any adverse reactions with your healthcare provider as soon as possible.

Cost

The cost of Saxenda and Ozempic depends on where you purchase it from, as well as how long you use it. For instance, Saxenda is recommended for 12 weeks of treatment, each month will cost around £250 – £299. Ozempic requires a small dose and will cost around £170 – £250 a month.

Is Ozempic stronger than Saxenda?

While they are similar in terms of efficacy, they differ in terms of how long the medication stays in the body. Saxenda has a shorter half-life than Ozempic, which means it is out of the system much quicker – a single dose will stay in your system for around 13 hours compared to seven days for Ozempic.

What is the difference between Ozempic and Saxenda?

Saxenda (Liraglutide) and Ozempic (Semaglutide) are both GLP-1 weight loss injections. Ozempic is given to people with type 2 diabetes, as it helps the body stimulate insulin secretion, resulting in lower blood sugar levels and reducing your risk of major cardiovascular events, like heart attacks and strokes, if you have heart disease. Saxenda has been licensed by the UK regulator (MHRA) as a medicine to help people lose excess body weight in conjunction with lifestyle changes, Ozempic does not have this license. Another main difference between them is their dosing schedules; Saxenda is given as a daily injection, while Ozempic is given once a week.

Do GLP-1 Agonists work?

Active ingredients such as liraglutide (Saxenda), and Semaglutide (Ozempic and Wegovy) are effective medications that have been studied to treat adults with obesity, the hormone binds to receptors in the brain, to increase insulin production, and decrease glucagon secretion which aids in lowing blood sugar levels, and slow down gastric emptying. Clinical trials suggest that GLP-1s are more effective at weight loss for adults compared to other weight loss drugs like Orlistat. A systematic review also showed that all five medications were more effective than the placebo at supporting weight loss. Moreover, the study revealed that participants taking liraglutide were twice as likely to achieve over 5% weight loss than those who took orlistat.

Further reading about Ozempic