£75 off your first month

Mounjaro vs Ozempic

Medically reviewed by


Ozempic and Mounjaro are both leading treatments for type-2 diabetes and chronic weight management. Early indications are that Mounjaro is more effective for weight loss. The medications are similar but work in slightly different ways, Ozempic is a GLP-1 agonist, whilst Mounjaro is a dual-acting drug that targets GLP and GIP receptors. Both medications are taken in the form of weekly injections and have similar potential side effects

When it comes to managing type 2 diabetes or chronic weight management there are several medications available. The two most common options today are the breakthrough drugs Ozempic and Mounjaro. In this article, we’ll delve into these two drugs’ differences, similarities, benefits, and risks. Whether you’re a patient, caregiver, or healthcare professional, understanding these medications can help you make informed decisions.

Differences Between Ozempic and Mounjaro

Both Ozempic and Mounjaro are prescription diabetes drugs designed to help control blood sugar levels in adults with type 2 diabetes. The medication also has applications for the treatment of obesity, with weight loss versions of the medication available under the name Wegovy and Zepound (in the UK Mounjaro is used for both applications)

Whilst the medications are similar, they have distinct characteristics:

Ozempic (active ingredient: Semaglutide): acts specifically on GLP-1 receptors. It helps manage blood sugar and reduces the risk of major cardiovascular events in patients with type 2 diabetes.

Mounjaro (active ingredient: Tirzepatide): is a dual-acting drug that targets both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors. Although it hasn’t yet received approval for cardiovascular risk reduction, clinical trials are ongoing.

What Is Zepbound?

In the US, Zepbound is the brand name for tirzepatide, the active ingredient in Mounjaro that is approved specifically for weight loss purposes. In the UK Mounjaro will be the brand name for the medication approved for treating type 2 diabetes and for weight loss.

Treatment Options: Ozempic vs. Mounjaro

The choice between Ozempic and Mounjaro depends on individual needs, preferences, and health conditions. During your online assessment, we’ll assess your medical history and recommend the best one for you.

Uses of Ozempic and Mounjaro

Both drugs help manage blood sugar levels, preventing complications such as heart disease, nerve damage, kidney failure, and vision loss. Regular A1C tests can gauge your long-term diabetes control.

Managing Diabetes with Ozempic and Mounjaro

These types of diabetes or weight management drugs are administered via weekly subcutaneous injections. Slowly increasing the dose can help manage common gastrointestinal side effects like nausea and diarrhoea.

Weight Loss Potential

Both Ozempic and Mounjaro may lead to significant weight loss. In clinical trials, Mounjaro demonstrated better efficacy in weight reduction, with 80% of users losing at least 5% of their body weight, and an average weight loss potential of between 10-15% of total body weight.

Side Effects

Common mild side effects include gastrointestinal side effects, such as nausea and diarrhoea, or short-term abdominal pain. Gradually adjusting the dose can mitigate these effects.

While rare, serious side effects may occur. Always consult your healthcare professional if you experience any unusual symptoms.


Both Ozempic and Mounjaro effectively lower blood sugar levels. Regular monitoring and adherence to treatment plans are crucial.

Switching Between Ozempic/Wegovy and Mounjaro

It is possible to switch between Ozempic or Wegovy and Mounjaro, however, it will require beginning on the entry-level dose and then gradually increasing over a few months until the maintenance dose is reached.

Choosing Between Ozempic/Wegovy and Mounjaro

Ultimately, the decision depends on your unique needs, lifestyle, and health goals. Our team will work closely with your to determine the best treatment option for you.

Remember, weight management involves a holistic approach—medication, diet, exercise, and regular check-ups. Stay informed, stay healthy!

Further reading about Mounjaro